The alarming prevalence of malaria and malnutrition among Davaoeños in the early 1900s prompted Rev. Robert F. Black to request the American Board of Foreign Missions to send medical missionaries to Davao. Dr. Charles & Mrs. Anne Sibley arrived in February 1908, establishing a small clinic near the Davao riverbank. Over time, this clinic evolved into a 36-bed hospital known as the Davao Mission Hospital.

In 1954, the management of the hospital was given to the United Church of Christ in the Philippines (UCCP). In that same year, a school of nursing was opened. However, in 1964 a fire razed both the school and hospital.

By 1968, the hospital and school relocated to a new site, enjoying prosperity in the 1970s and early 1980s, notably as the only hospital in Mindanao with a Burn Unit. Financial difficulties forced its closure in 1985, amidst broader hospital closures during the Marcos regime.

After seven years of dormancy, the institution reopened in 1992 under the name Brokenshire Integrated Health Ministries, Inc., signaling a new chapter in its history.

Meanwhile, AppleOne Properties, Inc. (API), a Cebu-based and homegrown property developer founded by enterprising couple Ray and Venus Manigsaca, established AppleOne Medical Group (AMG) their subsidiary and healthcare arm in 2020.

AMG went into a joint venture partnership with the United Church of Christ in the Philippines (UCCP) where Brokenshire Memorial Hospital (BMH) became the third hospital under its wing. In June 2023, a grand launch was held to present the newly named and rebranded Brokenshire Medical Center (BMC).